Thursday, October 31, 2019

Gulf Air Case Study Example | Topics and Well Written Essays - 2500 words

Gulf Air - Case Study Example Assets of the gulf air company have become manifold as compared to the time it started its business. (Gulf Air Official Website, 2010) The history of Gulf aviation relates back to the 1940s when a British pilot and entrepreneur named Freddie Bosworth started a company with the aim of providing air taxi services to the local customers and to the businesses. For ten years he was carrying on with the company with his small fleet of aircrafts and at the end of first quarter of 1950 he transformed his business into a private shareholding company with the name of Gulf Aviation. Therefore, it can be regarded as one of the oldest air carriers performing operations in the Middle East. After some time in 1951, the founder of the company died and it was all set to be sold to the big guns of the aviation industry. (Gulf Air Official Website, 2010) In the month of October of the year 1951 British Overseas Airways Corporation (BOAC) acquired a 22% stake in the Gulf Aviation and therefore became a major share holder in the company. After the purchase of stake of the Gulf Aviation by British Overseas Airways Corporation (BOAC) some of the updated and technologically advanced aircrafts were added to the fleet of the company as well as the company started its services to London city. Year 1973 is regarded as the most important year in the his... Thus by the acquisition of the shares of the company Gulf air became the national carrier of those four countries in the Persian Gulf. Moving further along the line in the same year, Gulf aviation achieved another land mark with the establishment of the subsidiary company of Gulf Helicopters. In the 1980s an increase in the trend of travelling by air was seemed in the world and the air travel was seemed to be the best commuting route in the world. With this opportunity Gulf airways also cashed in to make the best out of the bargain. It was the time of some real growth for the company and the company made the best out of the available opportunities. In the year 1981 Gulf Air became an IATA member and in the following year, it became the first International airline to land at Riyadh. With the progress of the company more and more aircrafts were also being added to the fleet of the company and in the year 1988 Boeing 767s were added to the fleet of the company and with the addition of Boeing 767s more services were offered to different customers of the different destinations. Gulf air also has the prestige of being the first Arab airline to fly directly to the continent of Australia. In the year 1994 Gulf air started receiving the airbus aircrafts and in the year 2000 took t he delivery of all of the remaining airbus aircrafts. In the meanwhile gulf air extended its services to the other parts of the world and the procedure of expansion did not stop. In the 1990s gulf air was down on profits and was not performing well as a corporate entity when the reign of the fleet and resources of gulf air was held in the hands of a newly appointed CEO of the company. In the year 2002 Mr. James Hogan became the president

Tuesday, October 29, 2019

Arts & academic Essay Example for Free

Arts academic Essay First of all, I have the diligence, determination, and aptitude to take on an Arts degree and make the most out of it. In such a large university, the ability to interact with peers and mentors both on academic and social levels is of also prime importance for survival. I am fortunately blessed with exceptional communication and interpersonal skills that allow me to be able to interact well in diverse groups. I can speak out my mind politely and explain my thoughts clearly and comfortably to make my peers and mentors understand my ideas accurately. However, the quality in me that I believe above all else would make me a success in a university Arts program is my strong vision of what I intend to be in life. This vision of mine has guided me throughout my education, keeping me in track with what I want out of life. My vision gives me an exact sense of personality, and through it I derive meaning and originality. I know what I want and I know that I have what it takes to make it happen, and that will eventually make me a success in your Arts program.

Saturday, October 26, 2019

The Impact Of Globalization On Engineering Companies

The Impact Of Globalization On Engineering Companies Globalization is one of the prominent features in the current trend of evolution for national economies. Companies and Nations can be offered with huge potential profits through globalization, but it is more complicated to implement because of widely differing expectations, standard of living, cultures and values as well as unexpected global cause-and-effect linkages. [1] Financial Globalization: Combination of sedentary financial system of a particular country with international organization as well as financial markets. Financial globalization acts as a safeguard against national shocks, an excellent system for the global allocation of resources in a more efficient way. [2] Production Globalization: Producers are getting more benefits from different cultures cheap labors all around the world, due to which world has become the global village. Companies prefer other parts of the world, where products are available at lower cost. Other reason for this is availability of natural resources in the country preferred facility provided by that country for foreign investments. This has a wide application addressed as production globalization, which needs higher technological knowledge countries with highly skilled people. [3] Competitive Globalization: In world where global competition is increasingly growing, nation has become more, not less, prominent. Basis of competition being shifted more more, the generation orientation of knowledge, role of nation has flourished. Competitive advantages is generated and approved through a highly confined process. Diversity in national values, culture, economic structures, institutions histories are all devoted to competitive success. Companies achieve competitive advantage through acts of innovation with broadest sense, including the new ways new technologies, this helps in perceiving an entirely new market opportunity. Globalization of Industry technology always helps in creating new winners also losers within the national economy for the competition to be more stronger. [4] Basic step of globalization is that, it is an intensified transference of exchange of things between pre-constituted units, being they are political, economic and cultural. Thus, Globalization signifies a process of change which originates at the level of unit in terms of unintended consequences of interaction between units. [5] Understanding of globalization can be accomplished in terms of range of values across the below mentioned four characteristics. When we see how far it reaches, broader geographical effects could be experienced in events and actions that take place. Globalization involves social, political economic activities being stretched and once it is implemented onto the process, one part of the world has an increasing effect on the situations in the other parts of world. http://t0.gstatic.com/images?q=tbn:ANd9GcTBMX7rPCg3IhrcLq9BVCHUHJAqtsGMIvMazbRNCChdlvBT6obQ Fig: Understanding the concept of globalization. (Google Images) Speed of global interconnections processes are uncertain. Results of developments in travel and communication technology have larger velocity. Impact of Globalization cannot be expected only in single type, but there are four different types of impact or outcome. Decisional Impact: What are the effects of globalizing processes? How do individuals, corporations, organization government make decisions? Institutional Impact: How the agendas of organizations and individuals are changed and structure their preferences regarding choices and influences? Distributive Impact: How is the distribution of way, wealth power within and among the countries changed? Structural Impact: How are the patterns behavior structured? This contains Social patterns, political patterns, economic patterns etc. [6] Source of lot of disputes over globalization involves different perceptions and the criteria employed in conceptualizing and defining it. Globalization of any market is at hand. The powerful force drive arises by comprising the commonality of the technology. This has three distinct abilities over the idea of Globalization, as explained below. (Source-International sociology p-180) Globalization as Transference implies that there is an exchange across the existing unit boundaries, units and systems but it is presumed to be identical to each other. Considering this interpretation, concept of globalization is an individuals ontology, which is logically open for methodological structuring possibilities. Hence takes place at an inside out direction in its flow. Following this logic of transference, we have an intense condensation of consequences today with larger systems being coupled over a corresponding inability to account for how the transformation of units might occur in process. So when there is a certain effect, it is possible to argue that globalization has a new geographical extension of state authority for pushing forward the process, while modern state remains as a globalization vehicle. (Source-International sociology p-184) Globalization as Transformation is a process which occurs at system level, affecting both system and identity of units in equal proportion. This concept is distinct from the first concept which defines the concept of globalization as a multidimensional process that takes place outside in. But there is continuity between them, wherein this second concept theorizes exactly about what is left out and rendered enigmatically by the first concept. Transformation preserves the distinction between unit and the system, but relativizes problematizes the system by turning it into a same level of units analyzed as its constituent parts. From this point of view, globalization might be made to look both necessary irreversible. (Source-International sociology P-186) Globalization as Transcendence implies those distinctions that together condition unit, system and dimension identity. Under this case, the Globalization is neither inside out nor outside in but rather a process that dissolves the divide between inside and outside. This concept is harder than that of transformation, because its concepts are beyond conventional theoretical categories. Globalization brings change not only to identify the units system, but also to the conditions of existence of objects of enquiry and the fields where they are temporalized as per the requirement of human knowledge, hence deriving the globalization forward in a dynamic irreducible form within particular dimensions. [5] Impact of Globalization: People rely more on market economy which has provided more faith in private capital resources, wherein International organizations started playing vital role in developing Industries giving fair impact to certain extent by giving varied opportunities. http://www.fotosearch.com/bthumb/ICN/ICN219/F0015451.jpg It helped in improving better productivity, hence improving standard of living. These are the positive impacts of Globalization over the Industries. The negative impact of globalization has thrown uncertain challenges like inequality across within industries along with market and environmental situations becoming worse. Industries being guarded by trade, investments financial issues, Liberalization process took the pace of Globalization. Financial globalization impact is huge in the composition of national international capital markets. The banking system was mostly stirred it had to experience the dis-intermediation. http://t0.gstatic.com/images?q=tbn:ANd9GcRrMsuwZagwCgZtdlvGarflv8WtMe8wwn7gLFHuIdM2SwzhSK38rA Positive Impact: Enhanced capital flow in each every country with which a country at any time is ready to face the financial confrontation. Capital flow between nations increased, which resulted in a well-organized way Improvement in the standard of living. Negative impact: Poor economy of any country would be affected by financial shocks of different countries. It would cause a severe disorder cost high for stock market turbulence, bank failures, corporate bankruptcies, currency depreciation, etc. For financially developed countries, financial globalization would reap out an extremely advantageous output. [7] Impact of Competitive globalization- Globalization has created fast growing market that stimulates new competition, demands higher level of efficiency requires true ability in supply chain development. Globalization of Industry technology promises to accelerate transnational integration cross-fertilization in engineering, technology and management. http://t1.gstatic.com/images?q=tbn:ANd9GcRnTBkbtQLFxjzqpMHpcT35VTbgrkxliOTxbhXoynzCICu388zGlg Fig: Competitive Globalization. (Google images) Competitive globalization of technical activities improves the difference and depth of current stock of world engineering and resources thereby provide greater stimulus to economic growth and technological development. [8] Impact of Production Globalization- Major measures initiated as a part of the liberalisation and globalisation strategy in the early nineties included scrapping of the industrial licensing regime, reduction in the specialization, correction of the ownership and the restrictive trade practice act, start of the privatisation programme, reduction in tariff rates and change over to the market determined exchange rates. http://t1.gstatic.com/images?q=tbn:ANd9GcQtzwR1iADc_QOa2sHQDTdvo4QSGRu-RHNJ5TT_SBE5RX8OZsTd Fig: Production Globalization (Google Images) India has to concentrate on five important areas to achieve the set goal. The areas like technological entrepreneurship, new business openings for small and medium enterprises, importance of quality management, new prospects in rural areas and privatisation of financial institutions. The manufacturing of technology and management of technology are two different significant areas in the country. [9] Globalization has many positive, contemporary enterprising aspects so as to increase the market access, capital access access to technology which improves the income employment opportunities. Intensified competition given through the transfer of investments, production rapid structural changes is the main principle of globalization. But if there is any pressure from globalization, it would affect the employment relations at regional, national international levels. Source- Human resource champions (Dave Ulrich) p-176 Important Effects of Globalization are raising competitiveness, relocation of economic activities, structural changes in economy, increased integration of global economic activities, improving technological advancements, increased innovation and skill mismatch. Impact of globalization varies considerably according to the organizational settings within each country; this framework influences the employer strategies business interests. Source- Human Resource Champions (Dave Ulrich) P-181 [10] Challenges of Globalization: The influence of globalization framework describes extent to which the firms respond to the opportunities threats evinced by Globalization; it is characterized by management initiatives to modify business tactics, marketing activities general series of tactical exercises in adroit move characterized by craftiness. Challenge : Earth Puzzle Prominent challenges of globalization are, competitive horizon is dominated by globalization. Globalization entails new ways of thinking about business; it may be regarding new markets, products, mind sets or competencies. Complex network of global centers of excellence is required for effective global competencies. Developing countries when integrated into global economy will present difficult challenges which are worth gaining. This is to be more significantly achieved by Industrial Developing countries. This provides an opportunity to improve the welfare over the long term. Wide ranging impact of globalization touches on many basic philosophical questions that give raise to different challenges. Globalization challenges to the traditional assumptions like profound quantitative increase in and intensification of social relations. [11] Detailed Description of Globalization impact over the service, product financial issues: To understand this whole concept, let us consider an example to be the context; wherein I have considered QUEST GLOBAL to explain this whole concept. http://www.quest-global.com/images/Quest_logo.gif Fig: Quest Global (questglobal.com) Growing is easy when company is small, but growing is not as easy when the same company grows bigger. Quest global is a leading provider of diversified engineering manufacturing services globally. It employs over 2000 professionals and has delivery centers in India, USA, Italy, Japan, Germany, France, Singapore, UK Spain. Quest Global is ranked World No.1 in Engineering Service Outsourcing by the Black Book of Outsourcing 2009. Quest Manufacturing specializes in precision manufacturing for aerospace, automotive and industrial components, power generation, large scale turnkey fabrication, design and manufacturing of test rigs, tooling, fixtures and gages. Quest has partnered with more than 10,000 companies around globe. It is a globalized company which is more stable in the systems management market for more than 20 years offering solid brand recognition. All over the world customers have selected Quest Global because of its product innovation passion, deep manufacturing expertise main focus over the consumer needs. [12] Milestones: At first, found Ajit Prabhu Aravind Melligeri in New York (Chairman and Chief executive Officer); after which Quest Global India was set up in Bangalore. It acquired a position of leader in providing Computer Aided Engineering consulting services, so as to enter the automotive domain. Finally by 2 years of hard work, it received its ISO 9001:2000 certification. Next step was getting appointed by Ansys, as its first-of-its-kind Centre of excellence in India. http://www.hfmametrony.org/Portals/0/Milestones_side.jpg Fig: Milestone (Google images) It signed up with United Technologies in Aero scope domain to provide good services. Wholly owned subsidiary was set up in Italy with its office at Florence, then in China with its office at Hangzhou. It received funding from Carlyle group that invested so as to improve its facilities to access new customers or markets. Wholly owned subsidiary was set up in Japan with its office in Yokohama City. Expanding of Aerospace manufacturing and Magellan Aero scope; Quest Global Manufacturing signs a 10 year strategic agreement. Both Quest Global and Magellan launch Indias first special processing facility for aerospace manufacturing. It received the award ISO 27001 for product development and engineering solutions promoters bought back the Carlyle stake. It achieved AS9100 Certification for aerospace manufacturing. Quest global becomes 1st India private sector player qualified globally to offer end to end solutions to EADS (European Aeronautic Defence Space Company). Quest manufacturing sets up a sheet metal fabrication facility for aerospace. Company got the notification from Government of India to lease out land at its precision engineering SEZ (Special Economic Zones) at Belgaum, India. It won competitive strategy leadership award from Frost Sullivan. It acquired ASE (Automotive Service Excellence) Technologies. It was awarded International Head Quarters Status by EDB (Economic Development Board), Singapore. Quest Globals commitment to quality and distinguished record in Engineering Consulting Services and Manufacturing has enabled it to establish a leadership position in most of its service offerings. With a best-in-class global leadership team, Quest Global is recognized as one of the largest pure play engineering services player, providing integrated product development and build solutions across the engineering services value chain. [13] After looking at all these achievements, we can understand how well this company is influenced by the production competitive efficiencies and has helped the company to grow in a well-developed manner globally all over the world. The vision of this company is to be most recognized respected global product development solutions partner to their customers. With respect to these visions, the company has its mission set which is to enhance the profitability of their customers through globalization. The core values for acquiring this mission are:http://www.eaaev.org/images/mission-statement.jpg Customer focus. Change championship. Teamwork. Accountability. To provide the globalized engineering service, they made use of crucial soft skills with the conclusion that, there is no one size fits to all solution for managing that satisfying level of end users. According to their opinion, customer relationship management communication were important for which the result would be seen in the milestones mentioned above. There is a tremendous change experienced in outsourcing characteristics which is aiming towards the tactical strategic benefits globally. Initially started with the availability of resources, which is now transformed into strategic initiatives like diversity, new capabilities catching up new markets trend for increase in productivity profitability of company. This has given major challenges ahead before achieving the goal that is set by the company. The solution for these major challenges was an excellent program managing framework, which helped in achieving the goals, maintain implement increasing benefits within the company. The foremost and key successful factor for the success of globalization is an effective efficient framework for managing the program in more productive manner. This process includes understanding customer needs, new value propositions based on the extracted needs, implementation of approved value propositions, value addition which helped in continuously improving. All these factors were achieved only through efficient coordinating with end users, management, sponsors, team members, supporting functions and suppliers for the relevant integration and control of various processes. Once the goals are being set into the framework, it is very important that clear objectives are to be defined for the whole process to be successful. In most of globalized environments all the parameters are framed for the growth support of the business, increase in the return of investment (margin velocity), continuously customizing the customer needs not losing any opportunities. The driving factor that contributes to pull push system required highly motivated and energetic leadership which plays the vital role and to react for changes that may occur drastically. All processes were made flexible, mature capable at all stages- program, project, task activity. Resulting output with standards were made acceptable by appearance, domain or the function. This success was made possible by establishing proper vision, mission, growth, n finally implementing these road maps with effective controlling changing these maps according to the customer requirements. SWOT analysis was more reliable for understanding the customer needs by filling the frequent gaps or risk analysis. To foster the quality, detailed process tools were used in the framework. Techniques like Manage by wandering around (MBWA) Manage by action items (MBAI) were used as a key drive to the success. This company has three different domains in which it has been successful all these years; they are Aerospace, Automotive Industrial products. When we just concentrate on how this company has improved globally within all these three domains individually, we get to know different characteristics from each and every domain. Looking into the Quest Manufacturing domain, it specializes in manufacturing products with precision, fabrication of sheet metal, tool design development, aerospace gauges fixtures, special processing, Industrial automotive verticals. Customized end-to-end solution is provided by flexible and modular approach from design to manufacturing; this reduces the cost value being increased. When exploring Quest Engineering domain, this company provides modified manufacturing engineering services. This company helps customers in different fields like industrial products, consumer electronics, in aerospace, health care, oil gas, power generation so as to cut product development costs, shortening lead times, maximizing the availability of resources, extending capacity by providing the complete support across the product life cycle from design modeling through analysis, prototyping, automation, data documentation, instrumentation controls, embedded systems development, manufacturing support, vendor management in-house precision machining. [14] They utilize a systematic approach called Global product development in order to bring resources together and manage from low cost regions to improve the customers profitability. It also uses SEZ for precision engineering which provides best-in-class facilities infrastructure for aerospace industry. C:UsersNamrathaDesktopashwiniCapture.PNG Fig (a): Increased Variation in achievement of the company in previous years. (Image from trusted source) Influence of financial, competitive production globalization on the relationship of Quest-Global and its client world-wide includes lot many significant factors. They are: Mindset We will do. There are 3 important mindset over which the company must focus for the productive outcome. They are It will happen, It may or may not happen or Its not going to happen. Chances of the companys success increases dramatically only when the process starts with We can do it mindset. Quality Delivery- Customers are God. No service business can sustain grow if it is not able to cherish its customers. Repeating business makes the issue possible. Quality always comes first, cost always comes next. Customer Focus Listen to the Customers. Customers are the vital players of any company are business, because they are the providers of Statement of work they are the individuals who give purchase orders. Hands on value driven It is not just the job we have to perform, but it is our mission. This must be the attitude of people involved in work in any company. This was the concern each every worker in this company which has increased the global position of this company to a very large extent as shown in the graph. [Information from trusted source] The other two important factors that are influencing the growth of this company worldwide drastically are Outsourcing Off-shoring. To make the product development cost minimum, to shorten the lead time, for the capacity to be extended, engineering resources to be maximized, the company use the technique of Outsourcing. To build deliver the products that are better and cheaper, to minimize the developing costs, to reduce the lead time, maximizing the resources, the technique of Off-shore engineering service is being used. This transforms the vendor company into a global force. Hence, this company is one of the top off-shore engineering companies for its resilience as a mature stable for their clients. Quests expertise in outsourcing engineering services ranges from concept design, detailing analysis, to product realization solution in all fields like aerospace, civil structures, power generation, industrial products, oil gas and transportation. They provide better, faster more value-optimized solutions through global product development framework. [15] Conclusion: By realizing their future goal, they clocked the revenue value fixed per every headcount in the company to certain value for certain time period. Even under that recession period that occurred in 2008, it grew its revenue by 15%. This had an effect of growth mindset, strong cost controls cautious spending which helped them in sailing over complications without making any undeniable choices across the board until this point of their global journey. http://t2.gstatic.com/images?q=tbn:ANd9GcQDS4AnZna9f_qOuJaY7tOS6hGlBctOF8PwL1Cu9Y78BkRXqjtV Fig: conclusion (Google images) They also used the strong key factors to stand strong over the global market; they are committed team members, focused strategy on strategic accounts, ability to adapt and meet the client needs. The company looks its future goals in a very promising way, due to which they are backed by strong bonding with their strategic accounts with Rolls Royce, Pratt Whitney, GE, Hamilton, Sundstrand, PG, EADS and several other emerging accounts. Their belief in saying, Past success does not guarantee the future success has helped them in achieving a drive of 40% growth every year. This result has created a dynamic market that has stimulated a strong competitive environment within the company and also the demands have reached a very high level of efficiency, this also requires true ability in supply chain development for both Financial and production impact. The Industry technology they are using, it promises to accelerate transnational integration cross-fertilization in all sectors of engineering, technical management. Bringing together and managing resources from low cost regions has helped them enhance their customers profitability. The usage of automation tool in production domain has helped the user in reducing the design cycle time considerably which provides with more accurate and detailed information. All the design rules and logics are now incorporated inside the master models which help in better knowledge management. The migration from 2D to 3D CAD platform has helped the user in reducing design errors and provides better visualization of the product. The standardization of the product structure and design practice and automating the same has given the user an edge over its competitors. [15] Their competitive globalization of technical activities has promised to improve the differences depth of current stock of world engineering and resources; thereby providing the greater stimulus to the economic growth technological development. [Information from trusted source]

Friday, October 25, 2019

The Mandala Archetype in Intertidal Life by Audrey Thomas :: Audrey Thomas Intertidal Life

The Significance of the Mandala Archetype in Intertidal Life      Ã‚  Ã‚  Ã‚  Ã‚   Audrey Thomas' novel Intertidal Life, is an account of a woman's struggle for Emmersonian self-reliance and identity. The main character, Alice Hoyle, is forced by her husband to undertake a perilous, painful, and chaotic journey into her subconscious, in order to find her "self". This struggle to obtain a new "self" identity and self-reliance is symbolized throughout the novel by the Jungian archetype of the Mandala; a circular image with a center that represents the: "wholeness of personality, [and] the center of the whole... It is the archetype of inner order; and it is always used in that sense, either to make arrangements of the many, many aspects of the universe-a world scheme-or to arrange the complicated aspects of our psyche into a scheme " (Psych,86). Therefore, in Intertidal Life, the Mandala is an archetype arising "when there is a great disorder and chaos in a [woman's] mind... It appears to bring order, showing the possibility of order and centeredn ess" (Psych,86) Alice Hoyle first experiences chaos and despair when Peter admits to Alice that he no longer loves Alice, and he wants to seek out and find himself. She interprets that the move to the island was simply a tact to get Alice easily out of Peter's life. As Alice says,"It's so strange. I've felt so close to you these last few months. I saw the new room, the move over here as something wonderful, a new beginning to our marriage. I guess what I saw as a sunrise, you saw as a sunset" (20). Moreover, as Alice realizes that her husband, Peter is having an affair with Anne-Marie, and her worldly values and ambitions are tossed upside down, she encounters her first Mandala type dream: one night, Alice had a dream of apples. She was holding Flora in her arms and people were pelting at them both with fruit... She was calling and calling for help (24).    In this dream, Alice is the focus of the center of attention, surrounded by people pelting her with apples. A schematic image is presented which is in the form of a Mandala. Out of this dream, she comes to the realization for the first time, that "the other woman" in Peter's life is Anne-Marie (24). Thus, this Mandala represents, that she is unwanted by Peter, must find away to protect herself from her emotions, and she must seek help, in redefining her life. The Mandala Archetype in Intertidal Life by Audrey Thomas :: Audrey Thomas Intertidal Life The Significance of the Mandala Archetype in Intertidal Life      Ã‚  Ã‚  Ã‚  Ã‚   Audrey Thomas' novel Intertidal Life, is an account of a woman's struggle for Emmersonian self-reliance and identity. The main character, Alice Hoyle, is forced by her husband to undertake a perilous, painful, and chaotic journey into her subconscious, in order to find her "self". This struggle to obtain a new "self" identity and self-reliance is symbolized throughout the novel by the Jungian archetype of the Mandala; a circular image with a center that represents the: "wholeness of personality, [and] the center of the whole... It is the archetype of inner order; and it is always used in that sense, either to make arrangements of the many, many aspects of the universe-a world scheme-or to arrange the complicated aspects of our psyche into a scheme " (Psych,86). Therefore, in Intertidal Life, the Mandala is an archetype arising "when there is a great disorder and chaos in a [woman's] mind... It appears to bring order, showing the possibility of order and centeredn ess" (Psych,86) Alice Hoyle first experiences chaos and despair when Peter admits to Alice that he no longer loves Alice, and he wants to seek out and find himself. She interprets that the move to the island was simply a tact to get Alice easily out of Peter's life. As Alice says,"It's so strange. I've felt so close to you these last few months. I saw the new room, the move over here as something wonderful, a new beginning to our marriage. I guess what I saw as a sunrise, you saw as a sunset" (20). Moreover, as Alice realizes that her husband, Peter is having an affair with Anne-Marie, and her worldly values and ambitions are tossed upside down, she encounters her first Mandala type dream: one night, Alice had a dream of apples. She was holding Flora in her arms and people were pelting at them both with fruit... She was calling and calling for help (24).    In this dream, Alice is the focus of the center of attention, surrounded by people pelting her with apples. A schematic image is presented which is in the form of a Mandala. Out of this dream, she comes to the realization for the first time, that "the other woman" in Peter's life is Anne-Marie (24). Thus, this Mandala represents, that she is unwanted by Peter, must find away to protect herself from her emotions, and she must seek help, in redefining her life.

Wednesday, October 23, 2019

Different Learning Theories Of Human Resource Development

Knowing a individuals larning manner enables larning to be orientated harmonizing to the preferable method. That said, everyone responds to and needs the motive of all types of larning manners to one extent or another – it ‘s a affair of utilizing importance that fits best with the given state of affairs and a individual ‘s acquisition manner penchants. Kolb ‘s larning theory sets out four different larning manners, which are based on a four phase larning rhythm. In this regard Kolb ‘s theoretical account is peculiarly elegant, since it offers both a manner to understand single people ‘s different acquisition manners, and besides an account of a rhythm of experiential acquisition that applies to us all. Diverging ( experiencing and watching – CE/RO ) Assimilating ( watching and believing – AC/RO ) Converging ( making and believing – AC/AE ) Accommodating ( making and experiencing – CE/AE ) Diverging people are able to look at things from different positions. They are sensitive. They prefer to watch instead than make, be givening to garner information and usage imaginativeness to work out jobs. They are best at sing concrete state of affairss several different point of views. Kolb called this manner ‘Diverging ‘ because these people perform better in state of affairss that require ideas-generation, for illustration, brainstorming. Peoples with a Diverging acquisition manner have wide cultural involvements and like to roll up information. They are interested in people, be likely to be originative and emotional, and be given to be strong in the humanistic disciplines. Peoples with the Diverging manner prefer to work in groups, to listen with an unfastened head and to have personal feedback. The Assimilating acquisition penchant is for a summarizing, logical attack. Ideas and constructs are more of import than people. These people require good clear account instead than practical chance. They do highly good at understanding broad runing information and forming it a clear logical format. Peoples with an Absorbing acquisition manner are less focussed on people and more interested in thoughts and abstract constructs. Peoples with this manner are more attracted to logically sound theories than attacks based on practical value. These learning manner people are of import for effectivity in information and scientific discipline callings. In formal acquisition state of affairss, people with this manner prefer readings, talks, researching analytical theoretical accounts, and holding clip to believe things through. For an illustration people who prefer the ‘Assimilating ‘ learning manner will non be comfy being thrown in at the deep terminal without notes and instructions. Converging people with a Converging learning manner can work out jobs and will utilize their acquisition to happen solutions to utile issues. They prefer proficient undertakings, and are less concerned with people and interpersonal facets. Peoples with a Converging acquisition manner are best at happening practical utilizations for thoughts and theories. They can work out jobs and do determinations by happening solutions to inquiries and jobs. Peoples with a Converging acquisition manner are more attracted to proficient undertakings and jobs than societal or interpersonal issues. A Converging acquisition manner enables high-quality and engineering abilities. Peoples with a Converging manner like to prove with new thoughts, to imitate, and to work with practical applications. The Accommodating acquisition manner is ‘hands-on ‘ , and relies on perceptual experience instead than logic. These people use other people ‘s analysis, and prefer to take a practical, experiential attack. They are attracted to new challenges and experiences, and to transporting out programs. They normally act on ‘gut ‘ inherent aptitude instead than logical analysis. Peoples with an Suiting acquisition manner will be given to trust on others for information than carry out their ain analysis. This learning manner is common and utile in functions necessitating action and enterprise. Peoples with an Suiting acquisition manner prefer to work in squads to finish undertakings. They set marks and actively work in the field seeking different ways to accomplish an aim. Peoples who like prefer to utilize an ‘Accommodating ‘ learning manner are likely to go defeated if they are forced to read tonss of instructions and regulations, and are unable to acquire custodies on experience every bit shortly as possible. However most people clearly display clear strong penchants for a given acquisition manner. The ability to utilize or ‘switch between ‘ different manners is non one that we should presume comes easy or of course to many people. Basically, people who have a clear acquisition manner penchant, for whatever ground, will be given to larn more efficaciously if acquisition is orientated harmonizing to their penchant. Honey and Mumford acquisition manners Honey and Mumford ( 1982 ) have built a typology of Learning Styles around this rhythm, placing single penchants for each phase ( Activist, Reflector, Theorist, and Pragmatist severally ) ; Kolb besides has a trial instrument ( the Learning Style Inventory ) but has carried it farther by associating the procedure besides to signifiers of cognition. Anonymous, ( 2010 ) There are four features of larning manners, Militant Theorist Pragmatist Reflector Militants involve themselves wholly and without unfairness in new experiences. They enjoy the here and now, and are happy to be dominated by immediate experiences. They are open-minded, non discrediting, and this tends to do them excited about anything new. Their doctrine is: â€Å" I ‘ll seek anything one time † . They tend to move first and see the effects afterwards. Their yearss are filled with activity. They tackle jobs by brainstorming. Equally shortly as the stimulation from one activity has died down they are busy looking for the following. They tend to increase on the challenge of new experiences but are bored with execution and longer term consolidation. They are gregarious people invariably affecting themselves with others but, in making so ; they seek to center all activities on themselves. For an illustration, those people who learn by making. Militants need to acquire their custodies dirty, to plunge in with both pess foremost. Have an open-minded attack to acquisition, affecting themselves to the full and without prejudices in new experiences. Brainstorming job resolution, group treatment, competitions and function drama, these are the activities of Militants. Theorists adapt and combine observations into complex but logically sound theories. They think jobs through in a perpendicular, bit-by-bit logical manner. They learn disparate facts into logical theories. They tend to be perfectionists who wo n't rest easy until things are tidy and fit into a normal proposal. They like to analyze and unite. They are acute on basic premises, rules, theories theoretical accounts and systems believing. Their doctrine awards reason and logic. â€Å" If it ‘s logical it ‘s good. † Questions they often ask are: â€Å" Does it do sense? † â€Å" How does this tantrum with that? † â€Å" What are the basic premises? † They tend to be detached, analytical and dedicated to rational objectiveness instead than anything subjective or equivocal. Their attack to jobs is systematically logical. This is their ‘mental set ‘ and they stiffly reject anything that does n't suit with it. They prefer to maximise certainty and experience uncomfortable with subjective judgements, sidelong thought and anything light-minded. For an illustration, scholars like to understand the theory behind the actions. They need theoretical accounts, constructs and facts in order to prosecute in the acquisition procedure. Prefer to analyze and synthesise, pulling new information into a systematic and logical ‘theory ‘ . Pragmatists are acute on seeking out thoughts, theories and techniques to see if they work in pattern. They positively search out new thoughts and take the first chance to research with applications. They are the kind of people who return from classs full with new thoughts that they want to seek out in pattern. They like to acquire on with things and act rapidly and confidently on thoughts that attract them. They tend to be impatient with ruminating and open-ended treatments. They are basically practical, down to earth people who like doing practical determinations and work outing jobs. They respond to jobs and chances ‘as a challenge ‘ . Their doctrine is â€Å" There is ever a better manner † and â€Å" If it works its good † . For an illustration, people need to be able to see how to set the acquisition into pattern in the existent universe. Abstract constructs and games are of limited usage unless they can see a manner to set the thoughts into action in their lives. Experimenters, seeking out new thoughts, theories and techniques to see if they work Reflector like to stand back to chew over experiences and detect them from many different positions. They collect informations, both first manus and from others, and prefer to believe about it carefully before coming to a decision. The thorough aggregation and analysis of informations about experiences and events is what counts so they tend to reschedule making unequivocal decisions for every bit long as possible. Their doctrine is to be careful. They are thoughtful people who like to see all possible angles and deductions before doing a move. They prefer to take a back place in meetings and treatments. They enjoy detecting other people in action. They listen to others and acquire the impetus of the treatment before doing their ain points. They tend to follow a low profile and have a somewhat distant, tolerant relaxed air about them. When they act it is portion of a broad image which includes the yesteryear every bit good as the present and others ‘ observations every bit good as their ain. For an illustration, people learn by detecting and believing about what happened. They may avoid jumping in and prefer to watch from the out of boundss. Prefer to stand back and position experiences from a figure of different positions, roll uping informations and taking the clip to work towards an appropriate decision.Learning TheoriesThe Behaviorist Approach Some of our acquisition comes approximately as a response to a stimulation. We are larning from our detectors. We react to something outside ourselves. If the consequence is good for us, we learn to respond in similar manner in a similar state of affairs, while if the consequence is bad, we learn non to make that once more. This is the basic thought of the Behaviorist Approach which can be traced back to the work of Pavlov ( 1927 ) who taught Canis familiariss to salivate at the sound of a bell. Behaviorist dressed ores on modifying behaviour by support. Behavior that is seen as positive or good is reinforced by wagess. For an illustration auto insurance is reduced if you do non do a claim. Most people have experienced both positive and negative support. We can see that behaviourist larning theories have their strengths. However, this attack to acquisition has been critized as mechanistic and be givening to concentrate merely on certain behaviour. There is grounds to propose that support may necessitate changeless topping-up to stay effectual. Anonymous, ( 2010 ) The Cognitive Approach If some of our acquisition is reactive, some acquisition can besides be described as positive. That is we seek out information and attempt to do sense of it in order to understand better our universe and our topographic point in it. This is the footing of cognitive theories of acquisition, which make usage of the work of research workers such as Kohler ( 1925 ) and Piaget ( 1950 ) . Kohler worked with apes and Piaget concentrated on kid development, but their consequences have been applied more widely. For the cognitive, the cardinal characteristic of human existences for acquisition is that we are intelligent searchers. Harmonizing to cognitive attacks, we invariably find that our experience of the universe does non rather fit the manner we see the universe, and we try to make something about the misfit. We seek new information, we adjust our position of the universe, and we may make a new manner of seeing the universe. There are clear connexions here with some of the elements we noted earlier in the different phases of the acquisition procedure. The Social Learning Approach The societal acquisition theory proposed by Albert Bandura has become possibly the most of import theory of larning and development. While ingrained in many of the basic constructs of traditional acquisition theory, Bandura believed that direct support could non account for all types of acquisition. His theory added a societal component, reasoning that people can larn new information and behaviours by watching other people. Known as experimental acquisition ( or patterning ) , this type of acquisition can be used to explicate a broad assortment of behaviours. Psychology, ( 2010 ) Basic Social Learning Concepts 1. Peoples can larn through observation. Observational Learning In his celebrated â€Å" Bobo doll † surveies, Bandura established that kids learn and reproduce behaviours they have observed in other people. The kids in Bandura ‘s surveies observed an grownup moving sharply toward a Bobo doll. When the kids were subsequently allowed to play in a room with the Bobo doll, they began to reproduce the aggressive actions they had antecedently observed. Bandura identified three basic theoretical accounts of experimental acquisition: A unrecorded theoretical account, which involves an existent single representative or moving out a behaviour. A verbal instructional theoretical account, which involves descriptions and accounts of a behaviour. A symbolic theoretical account, which involves existent or fictional characters exposing behaviours in books, movies, telecasting plans, or on-line media. 2. Mental provinces are of import to larning. Intrinsic Support Bandura noted that external, environmental support was non the lone factor to act upon acquisition and behaviour. He described indispensable support as a signifier of internal wages, such as pride, satisfaction, and a sense of achievement. This accent on internal ideas and knowledges helps link larning theories to cognitive developmental theories. While many text editions place societal larning theory with behavioural theories, Bandura himself describes his attack as a ‘social cognitive theory. ‘ 3. Learning does non needfully take to a alteration in behaviour. While behaviourists believed that larning led to a lasting alteration in behaviour, experimental acquisition demonstrates that people can larn new information without showing new behaviours. The Modeling Procedure Not all observed behaviours are efficaciously learned. Factors affecting both the theoretical account and the scholar can play a function in whether societal acquisition is successful. Certain demands and stairss must besides be followed. The undermentioned stairss are involved in the experimental acquisition and patterning procedure:Attention:In order to larn, you need to be paying attending. Anything that detracts your attending is traveling to hold a negative consequence on experimental acquisition. If the theoretical account interesting or there is a fresh facet to the state of affairs, you are far more likely to give your full attending to acquisition.Retention:The ability to hive away information is besides an of import portion of the acquisition procedure. Retention can be affected by a figure of factors, but the ability to draw up information subsequently and move on it is critical to experimental acquisition.Reproduction:Once you have paid attending to the theoretical accoun t and retained the information, it is clip to really execute the behaviour you observed. Further pattern of the erudite behaviour leads to betterment and skill promotion.Motivation:Finally, in order for experimental acquisition to be successful, you have to be motivated to copy the behaviour that has been modeled. Support and penalty play an of import function in motive. While sing these incentives can be extremely effectual, so can detecting other experience some type of support or penalty. For illustration, if you see another pupil rewarded with excess recognition for being to category on clip, you might get down to demo up a few proceedingss early each twenty-four hours. Psychology, ( 2010 )Learning CurveA acquisition curve is a graphical representation of the altering rate of acquisition ( in the mean individual ) for a given activity or tool. Normally, the addition in keeping of information is sharpest after the primary efforts, and so on a regular basis evens out, intending th at less and less new information is retained after each duplicate. The larning curve can besides stand for at a glimpse the initial trouble of larning something and, to an extent, how much there is to larn after early cognition. For illustration, the Windows plan Notepad is highly simple to larn, but offers little after this. On the other extreme is the UNIX terminus editor VI, which is hard to larn, but offers a broad array of characteristics to get the hang after the user has figured out how to work it. It is possible for something to be easy to larn, but hard to get the hang or hard to larn with small beyond this. Wikipedia, ( 2010 )

Tuesday, October 22, 2019

Class and Its Derivatives

Class and Its Derivatives Class and Its Derivatives Class and Its Derivatives By Mark Nichol The Latin noun classis, meaning â€Å"category† or â€Å"fleet† or referring to a group of citizens called up for military duty, is the source of the word class and others derived from it, which are listed and defined in this post. In educational contexts, class pertains to a group of students (whether those enrolled in a particular course or in the same grade level), a course of instruction, or a meeting of such a course. In a socioeconomic sense, it refers to a stratum of social standing, in science it denotes a level of organization of living things, and in general it refers to a category. The verb class, meaning â€Å"categorize,† is used in the scientific and general senses, and the word serves as an adjective, including in the idiom â€Å"class act,† which offers an additional meaning equivalent to the adjective classy, meaning â€Å"elegant,† â€Å"refined,† â€Å"skillful,† or â€Å"well mannered.† The adjectives first-class and second-class literally pertain to a high and a moderate quality of accommodations during travel, respectively, and figuratively denote superiority and inferiority, respectively. (High-class and low-class are equivalent to the latter meanings.) The nouns â€Å"upper class† (pertaining to the affluent), â€Å"middle class† (those living a moderate lifestyle), and â€Å"lower class† (those with low incomes or none at all) also serve as adjectives. â€Å"Leisure class† refers to people wealthy enough that they are not required to work for a living. â€Å"Working class† describes people employed in jobs that do not necessarily require higher education as an employment qualification. (Underclass is similar in meaning.) The pejorative, condescending expression â€Å"chattering classes† alludes to political opponents who utter what are considered meaningless opinions. Terms related to education with the root class include classmate, referring to one enrolled in the same course or grade level, and classroom, denoting a room used for instruction. An upperclassman is a student in one of the two higher grade levels in secondary or postsecondary education (often identified as a junior or senior), and an underclassman has a standing in one of the two lower levels (a freshman or a sophomore.) (The female equivalents upperclasswoman and underclasswoman are rare.) Several terms based on class allude to a high quality of artistic achievement. Classic, as a noun or an adjective, alludes to something authoritative or typical, or long considered an exemplar of great achievement or high quality, though by extension it now describes anything memorable, even if merely because it is highly amusing or ironic. (â€Å"Did you see her trip and fall into her wedding cake? That was classic!†) â€Å"The classics† describes either the extant works of celebrated Greek and Roman writers or a nebulous body of more recent literature that those who claim to be erudite should be acquainted with. A style of architecture or art, including literature, that calls to mind the characteristics of corollary Greek or Roman achievements is referred to as classicism. Neoclassicism is an esthetic form influenced by classicism, and postclassicism denotes one that follows a period understood to be one of classicism. (The adjectival forms are classical, neoclassical, and postclassical.) Classical music is a form of sophisticated musical expression as distinct from simpler music such as folk or jazz. In terms of quality or social strata, other words derived from class include classism, meaning â€Å"discrimination based on class,† as well as classless, which can refer either to a lack of sophistication thought to be the result of being raised in an inferior class (dà ©classà © is a synonym for this sense adopted directly from French) or to someone who lives outside of class-based strictures or to freedom from class distinctions. Words pertaining to categorization include the verb classify and the adjective classified, which simply means â€Å"arrange into classes† but is also part of the standing phrase â€Å"classified ads† (sometimes truncated to â€Å"classifieds), which refers to advertisements divided into categories; the adjective also describes something categorized as being of restricted to a certain audience, such as a government document. Something that can be classified is classifiable, and classificatory describes something pertaining to classification. To outclass is to outperform someone considered to be in the same class, and a subclass is a further division of a category. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Vocabulary category, check our popular posts, or choose a related post below:Creative Writing 101Top 11 Writing Apps for iOS (iPhone and iPad)â€Å"Least,† â€Å"Less,† â€Å"More,† and â€Å"Most†

Monday, October 21, 2019

Informative Abstract Example Essays

Informative Abstract Example Essays Informative Abstract Example Paper Informative Abstract Example Paper Essay Topic: Informative Ronnie Green Informative Abstract June 28, 2011 Image gap is the difference between how a person wants to look and sound compared to how they are actually viewed by others. Projecting your desired image can build trust and is critical to successful communication. Projecting an inappropriate image, however, can erode trust and cause others to doubt your abilities. Four components of your overall image are your projected first impression, your depth of knowledge, your breadth of knowledge, and your enthusiasm. Your projected first impression is the initial impact you make on another person due to your dress, voice, grooming, handshake, eye contact, and body language. First impressions tend to be long lasting and difficult to overcome. To create a positive first impression, you should have a firm but not overpowering handshake. Sit and walk in a straight yet relaxed manner. Maintain high standards of personal hygiene and grooming. Speak clearly while naturally varying your tone and volume. Finally, dress appropriately for your job responsibilities and work environment since skillful dressing can evoke positive responses to your personality. Depth of knowledge refers to how well you know your area of expertise. Demonstrating your depth of knowledge can project credibility and demand respect. You can develop depth of knowledge by studying company policies and industry standards. You can also take advantage of training programs offered by your company. Breadth of knowledge reflects your ability to communicate with others on topics outside your area of expertise. Breadth of knowledge allows you to more easily develop rapport with others. It will also allow you to increase your circle of influence with various types of people. You can increase your breadth of knowledge by reading a variety of books and magazines, watching and listening to a diverse selection of television and radio programs, and interacting with a wide array of individuals. If you encounter a person whose interests you are not familiar with, you can quickly gain knowledge and show interest by asking questions. An appropriate level of enthusiasm demonstrates your sincere interest in a subject and desire to accomplish a task. Enthusiastic people tend to work harder, longer, and more accurately than those who are not enthusiastic. Additionally, your enthusiasm, positive or negative, will spread to those around you. These elements help dictate the response you receive from others in everyday interactions. A positive response demonstrates successful interpersonal relations. It will also foster open, honest, and trusting communications.

Sunday, October 20, 2019

The Opium Wars essays

The Opium Wars essays The Opium Wars were really not about Opium. Instead, they were a result of Western (especially British) desires to further their economic interests in China. In addition to rigid restrictions under the Canton System of trade, the British suffered from a negative trade deficit with China. Therefore, I feel that Opium was only a symptom of a much larger problem, that problem being that the Westerners wanted a virtually unrestricted trading environment that served their interests. The Chinese had little use for Western goods for as they saw it, China was the Middle Kingdom, the center of everything civilized. The opposite was true of Westerners. Westerners, especially the British, loved tea. In addition to tea, they also purchased large quantities of silk and rhubarb (Hsu, 150) along with beautiful Chinese porcelain. This deficit was reduced once the sale of the Indian Patna and Malwa Opium commenced around 1820. Even though opium trade was forbidden by imperial decree, the Opium trade continued and flourished, especially along Chinas South Coast. Addiction was so bad by the 1830s that most men under 40 had smoked Opium at one time in their lives. The number of people addicted during that decade is estimated to be around 12 million. In order to compensate for the trade deficit, the Chinese exported silver, which began to drain the treasury. In the words of one government official "If we continue to allow this trade to flourish, in a few dozen years, we will find ourselves not only with no soldiers to resist the enemy, but also with no money to equip the army ( Chesneaus Jean, 55). Even though Opium is a drug and it is bad, I believe that the Chinese would have had a fit over any product that was draining their economy and benefiting the barbarians. If Opium was so evil and bad, why were there so many people in government and military ranks addicted to it ...

Saturday, October 19, 2019

Biblical narratives Coursework Example | Topics and Well Written Essays - 250 words

Biblical narratives - Coursework Example Narratives genre enables a clear understanding and even communicating the bible message that correspond a form of story and personal testimony which is sometimes characterized by holy script. This is, of course, fundamental modernity that allows communication among human beings. In fact the Old Testament presents a true story of salvation and powerful recital that gives substance of liturgy, catechesis and faith. In itself, the proclamation of any Christian kerygma amounts to absolutely telling of life, death and later resurrection of Jesus Christ (Fee, 2011, p. 106). According to Free and Stuart, this appears to be narrative in nature as the gospel accounts it. With respect to this narrative approach, it helps in distinguishing between analytical and theological reflection of everything that life has. The most of analyst methods which are proposed today begin from study of the ancient model of some narratives genre, while others base themselves on present day analogy in one way or another (Fee, 2011, p. 106). This is contrary to the scriptural interpretation which is aimed at reflecting the present, past and future scenarios that believers go through. Instead of reading the entire bible narrative in order to understand the major theme, purpose, flow and plot of the narrative, majority of us just read through to catch the drama, as well as the power of the story. We simply assume that we have seldom grown up with the old testament of gospel and we are familiar with everything. What has to be remembered is that, these biblical narratives were written by authors who were inspired with the Holy Spirit and should not just be interpreted as an ordinary story in its literal meaning. Since narratives do not only teach each doctrine directly, it does not necessarily mean that one must not learn some doctrine from biblical narratives. Rather than teaching

Friday, October 18, 2019

Racial Differences in America Essay Example | Topics and Well Written Essays - 1000 words

Racial Differences in America - Essay Example This paper suggests some courses of action to achieve racial equality in the future of United States of America. My view on the course of action to take is as a result of the historical lessons as espoused by Franklin. History of Racial Inequality in America. Since the first settlers landed on the New World, issues of equality and justice among races have been and continue to be debated strongly, often violently. Right from the beginning when the white settlers encountered the Native Americans, to the latter European settlers and to the African slaves bonded to serve their white masters, inequality existed. Negroes languished lowest on the equality ladder, even those that had never been enslaved. This was due to both the laws of the land and customs of the enslavers. All these despite the fact that Negro labor is what brought development in most parts of America. It was their hard labor that made it possible to farm, mine, explore the interior of the continent and build infrastructur e. It was difficult to end slavery since the trade in humans brought profits to the shippers and merchants and most other traders. Meanwhile, the white colonialists also felt that paying taxes to the British Monarchy was enslaving them. By mid 18th century, they were clamoring for emancipation from British rule that forced them to remit taxes. They, white settlers, were also against British policy of condemning and outlawing slavery and the slave trade as a whole. Among them were those who felt it was hypocritical to want freedom from British bondage while they owned slaves. Slaves too began voicing their need for freedom from the settlers who wanted the same from their colonial masters. Thomas Jefferson, a co-author of the declaration of independence and a slave-owner himself, attempted to appeal to the British crown to abolish slavery and slave trade and declare universal equality. Sadly, he also was of the opinion that the black man was physiologically and intellectually inferior to the white man. The white patriots later expunged these sections from the draft declaration (Franklin 14). The abolition of slavery in the Northwest Territory in 1787 marked a significant step in securing the Negroes’ inalienable rights as human beings. Still, there were calls to deport slaves as soon as they were emancipated, for most settlers still found it hard to regard them as equals. They thought that the manumitted Negroes would cause chaos and it would be safer to return them to Africa than live with them. This proved an insurmountable task due to the sheer numbers of slaves. Free blacks lacked suffrage, and even though they were no longer bound by slavery, they lived as pariahs in society. They also had to pay higher taxes than whites, prohibited from testifying against whites in court, serving in the military or even owning real estate. Such injustices sowed the seeds of revolution and demands for equality and human rights. Inequality Today. In the eighteenth cen tury, the black slave was a property just like a table in the living room. Property could not be given away freely for that meant economic loss. The white settlers were against slave emancipation mainly due to economic reasons. Apart from losing property, freeing a slave meant the loss of cheap manual labor. The white settlers would have to pay for laborers to till their farms, build their bridges and carry loads. A free former slave also meant competition for

Niccolo Machiavelli Essay Example | Topics and Well Written Essays - 500 words

Niccolo Machiavelli - Essay Example Machiavelli shows experiences are not merely limited to explanation of similarity but also offers an outlook and to a certain degree predictability of change not only in human conditions but also in circumstances of human life. Therefore, the present and the past remain in nature the only guideline for the occurrence of future events. The essay discusses this statement. Machiavelli statement depicts history as taking on educational role since there are similarities in present, past and future events. For instance, in index funds decision regarding where an entrepreneur can invest is essential. It is difficult to make a wise decision without adequate understanding of the long-term historical risks as well as returns in different indexes. Being able to gain the necessary understanding entails establishing the various indexes available for investment. Through remarkable understanding regarding the prolonged historical risks as well as returns of various indexes, investors are able to comprehend the way to apportion indexes according to their individual risk capability. Naturally, investors are interested in investing on index portfolios, which provide the maximum return rate in the risk level matching the investor’s risk capacity (Hebner 166). Rational prediction in Machiavelli’s statement relies on the existence of proper links that connect predictive claims to input data, which in return provides the justification. The input data can only be available by understanding the past. Machiavelli believes that social conditioning never results in different responses because men are not byproducts of the diverse environments but through historical events that are the same and generate similar response in both present men and men of the past. Through history, Machiavelli manages to show that it elicits sameness that allows creation of universal laws for behavior and explanation (Rigney & Douwe

Evaluate the applicability of Tedlow's three stage model to the Essay

Evaluate the applicability of Tedlow's three stage model to the product-market sector of your choice - Essay Example In most emergency rooms, the treatment would have cost over $500. Even better, this clinic accepted Ms. Charles’ insurance. If you also factor in the fact that Ms. Charles could do her grocery shopping in that store while she waited for the pharmacy to fill a prescription for her, you suddenly have a very convenient trip (Rowland). While Ms. Charles visited a clinic that was staffed by a doctor, most of the clinics inside Wal-Mart, Target, and other big-box retailers feature nurse practitioners, who can write prescriptions in most states. The retailers do not enter the world of medical care as part of their own corporate activities, but simply lease the space to clinics. It’s not just the big-box retailers who are looking into clinics, either. Because of the losses due to mail-order pharmacies and big-box retail sales, drugstore chains are also opening clinics. Rite Aid Corp., Brooks Eckerd Pharmacy, and Osco Drugs are all entering partnerships to open clinics, and Walgreen Co., the pharmacy chain with the most sales volume in the United States, is also negotiating a deal to have Take Care Health Systems LLC operate clinics in some of their retail locations. The retailers who are leasing space to these clinics hope to make profit not just from the leases themselves, but from the ancillary shopping that will go on while people wait for their prescriptions to be filled, or wait for their appointment to be called. It is similar logic to those grocery stores and big-box retailers who have leased space to banks, hair salons, postal service kiosks, and fast-food restaurants (Moewe). Doctors’ associations, as one might expect, have raised objections about the possible problems with this type of medical care. While nurse practitioners can treat a number of simple illnesses, the American Medical Association notes that simple symptoms can be indicative of any number of serious illnesses. The primary concern of

Thursday, October 17, 2019

Youth Violence In Schools Essay Example | Topics and Well Written Essays - 750 words

Youth Violence In Schools - Essay Example en all the basic necessities in their lives including good foundation for their social and emotional needs (Haapasalo & Pokela, 1999; Goldhagen & Lansdown, 2008). It is also important to consider that without this proper care, there is a great absence of providing other needs that children can use when they grow as young adults. The young adults face different situations in their lives including different problems. One of these is youth violence in school. Youth violence is a prevalent issue in the world. However, this issue is highly integrated not just within school premises, but inside home. Thus, youth violence in school is a problem in the society that starts from home. Youth violence in school is a problem in the society that starts from home because it is a place that has become an integral part of one’s life where values, characters and personalities are formed (Harden & Whittaker, 2011). In there, there are parents who always have the chance to influence their children. It is their obligations to show to their children the good values, characters and personalities to live by. Failure of these parents to show these will usually result to undesirable expectations. In most of the time, children are always blamed about their being foolish or hard headed when in fact; the bottom line of it all is the failure of parents to show good influence at home. In the same way, young adults usually find themselves blamed about their own actions when in fact, the very foundation of the problem starts from the kind of influence they receive at home from their parents. Youth violence is a problem that starts from home because it depends on the level of communication parents invest in their children’s lives. Aside from setting a good influence of parents for their children, it is tested and proven that a good communication between them would also work out. Children who receive constant communication with their parents have many things to learn (Tates & Meeuwesen, 2000).

Database Applications Research Paper Example | Topics and Well Written Essays - 500 words

Database Applications - Research Paper Example Arnisted2 (2001) categorizes and differentiate these softwares as family software and business software depending upon contact information, medical records, hobbies, educational records, wish lists, diary, journal, etc. Groupware, also called as collaborative software, is an elementary component of a field of study known as Computer-Supported Cooperative Work or CSCW3. A few examples can be listed as Microsoft Exchange, MediaWiki, WetPaint, and ClassroomLive2.0 and so on. 2) What kinds of things do groupware users do with data? How does that data have to be treated? In general there are three functions of groupware, enabling human to converse, transact and collaborate the ‘information and knowledge’ (also termed as data), about self and others. Groupware users use data into several ways and for several purposes including sharing, analyzing, creating, discussing, debating, planning, summarizing, concluding, etc. Since data is a unique significant aspect for human individu al/group identity, this must be used and shared with utmost care. This can be used for semantic purposes, and, sometimes, can be misused too. Ample privacy and security of the data should be of prime concern while treating with this data. 3) Who pays the costs of groupware deployment? Who receives the benefits? Groupware can be freeware or shareware or authoring.

Wednesday, October 16, 2019

Evaluate the applicability of Tedlow's three stage model to the Essay

Evaluate the applicability of Tedlow's three stage model to the product-market sector of your choice - Essay Example In most emergency rooms, the treatment would have cost over $500. Even better, this clinic accepted Ms. Charles’ insurance. If you also factor in the fact that Ms. Charles could do her grocery shopping in that store while she waited for the pharmacy to fill a prescription for her, you suddenly have a very convenient trip (Rowland). While Ms. Charles visited a clinic that was staffed by a doctor, most of the clinics inside Wal-Mart, Target, and other big-box retailers feature nurse practitioners, who can write prescriptions in most states. The retailers do not enter the world of medical care as part of their own corporate activities, but simply lease the space to clinics. It’s not just the big-box retailers who are looking into clinics, either. Because of the losses due to mail-order pharmacies and big-box retail sales, drugstore chains are also opening clinics. Rite Aid Corp., Brooks Eckerd Pharmacy, and Osco Drugs are all entering partnerships to open clinics, and Walgreen Co., the pharmacy chain with the most sales volume in the United States, is also negotiating a deal to have Take Care Health Systems LLC operate clinics in some of their retail locations. The retailers who are leasing space to these clinics hope to make profit not just from the leases themselves, but from the ancillary shopping that will go on while people wait for their prescriptions to be filled, or wait for their appointment to be called. It is similar logic to those grocery stores and big-box retailers who have leased space to banks, hair salons, postal service kiosks, and fast-food restaurants (Moewe). Doctors’ associations, as one might expect, have raised objections about the possible problems with this type of medical care. While nurse practitioners can treat a number of simple illnesses, the American Medical Association notes that simple symptoms can be indicative of any number of serious illnesses. The primary concern of

Tuesday, October 15, 2019

Database Applications Research Paper Example | Topics and Well Written Essays - 500 words

Database Applications - Research Paper Example Arnisted2 (2001) categorizes and differentiate these softwares as family software and business software depending upon contact information, medical records, hobbies, educational records, wish lists, diary, journal, etc. Groupware, also called as collaborative software, is an elementary component of a field of study known as Computer-Supported Cooperative Work or CSCW3. A few examples can be listed as Microsoft Exchange, MediaWiki, WetPaint, and ClassroomLive2.0 and so on. 2) What kinds of things do groupware users do with data? How does that data have to be treated? In general there are three functions of groupware, enabling human to converse, transact and collaborate the ‘information and knowledge’ (also termed as data), about self and others. Groupware users use data into several ways and for several purposes including sharing, analyzing, creating, discussing, debating, planning, summarizing, concluding, etc. Since data is a unique significant aspect for human individu al/group identity, this must be used and shared with utmost care. This can be used for semantic purposes, and, sometimes, can be misused too. Ample privacy and security of the data should be of prime concern while treating with this data. 3) Who pays the costs of groupware deployment? Who receives the benefits? Groupware can be freeware or shareware or authoring.

The evangelist included the signs in order to make people believe Essay Example for Free

The evangelist included the signs in order to make people believe Essay There is much speculation from scholars as to why John chose to include the signs, which are unique to the fourth gospel. Broadly speaking, there are two main views. The first is that the signs were intended purely to be accurate accounts of Jesus miracles, featuring historically and topographically factual details. The second, and perhaps more widely held, is that John had an evangelistic purpose in mind when he wrote the signs: he wanted to make his readers believe. John chooses to use the word semeia, meaning signs, rather than the dunameis (mighty act, used in the synoptics) to denote the miracles that Jesus performs. Whereas act is a word firmly rooted in a particular place and timeframe, the word sign evokes the idea of the miracles pointing to something else, or foretelling a future event. It implies a greater role and purpose to Jesus miracles than the acts themselves, a divine scheme, thus helping the reader see the link between Jesus (who looks like an ordinary person) and the Father. Johns choice of words alone suggests he wanted the signs to be seen by the reader in a theological light, not an historical one. In fact, John explicitly says of the signs: These are written that you may believe that Jesus is the Christ, the Son of God, and that by believing you may have life in his name. (John 20:31) Tasker mentions that some scholars in the past believed this statement to be a later addition to the gospel, by a later author or redactor. However, since there is no evidence for this, it is necessary to assume that the original author of Johns gospel wrote the statement themselves. For this reason, it cannot be denied that one of, if not the, main purpose of the signs is to fulfil an evangelistic role. Some might argue that there are parts of the signs that seem to contradict this purpose. For example, neither the third or fourth sign ends with true faith from those involved. In the third sign, the Healing at the Pool, the crippled man does not embrace Christs teachings but instead goes straight to the Jewish authorities, and even tries to shift blame onto Jesus for disregarding the rules of the Sabbath. At the end of the fourth sign, the Feeding of the 5,000, the crowd tries to make Jesus king by force. They do not understand that, as Sanders and Mastin put it, Jesus was a king, buthis kinship was not of this world. Both signs three and four end in the same way: with Jesus quietly leaving the scene, because he has failed to inspire people to faith as he had hoped. Although these signs do result in negative outcomes, they are quite possibly a tool John has deliberately employed to help his readers understand the nature of faith. By giving clear examples of people not recognising Christ as the Messiah, either by falling back on the comfortable familiarity of Judaism (as did the crippled man) or misunderstanding the nature of Jesus authority (like the crowd that were fed), the reader is better able to understand what it means to believe. They can also empathise with Jesus frustration at the fact that he is not producing the effect he intended, even having performed great miracles before peoples eyes, and so begin to know Jesus as a person as well as his divinity. Another objection to the statement in the title is that John includes many details that seem to serve no other purpose than to document the particulars of the sign. For example, in the third sign, there is mention of the Sheep Gate at the Pool in Bethsaida, the five stone colonnades and the fact that the man in question had been crippled for 38 years. However, these are not necessarily included by John for the sake of being historically and topographically accurate. Some details could be symbolic. For example, Marsh suggests that the 38 years could be a deliberate parallel to the 40 days that Moses spent wandering the desert. This parallel might be intended as a subtle message to the reader that Christ has fulfilled Judaism, making it good, just as Jesus makes the crippled man better in the sign. The details that John includes in the signs may also be a way of validating them and convincing the reader that Jesus miracles did take place. It seems that the title claim is justified, and that Johns main purpose for the signs was in fact to make his readers believe. Not only is it explicitly stated in John 20:31, but there is evidence for it throughout the signs. Whilst it appears at first that the gospel being a theological piece of writing and it being an accurate account are mutually exclusive, the two attributes do overlap. As Marsh notes, the historical and topographical details in John often give rise to symbolism and provoke theological thought, and can be just as important as the fictitious component of the signs in encouraging faith in the reader.

Monday, October 14, 2019

Monoclonal Antibodies as a Therapeutic Approach for Cancer

Monoclonal Antibodies as a Therapeutic Approach for Cancer INTRODUCTION Monoclonal anti-body cancer therapy is one of the most suitable therapeutic approach for hematologic malignancies and solid tumours for the past several years. This therapy of monoclonal anti-body join target cell, increase immune system, kills affected cells and slows tumour growth in patient. It is a laboratory produce mixture of homogenous anti-body molecules with empathy towards a particular antigen being generated by using a hybridoma by combining a B-cell with a single lineage of cells containing a specific antibody gene. A host of similar cells are produced that secrete the same anti-body. Owing to its specificity and high reproducibility, MAbs are more advantageous over polyclonal antibodies. MAbs are more often used in variety of applications like, research and diagnosis, therapeutic tools in cancer and immunological disorder, pharmacy, etc, as such are in huge demand in industry. Due to its high specificity, MAbs are increasingly used for basic immunological and molecular r esearch and have proven desirability. They are used in human therapy, cancer therapy, diagnosis of disease, commercial protein purification, suppressing immune response, hormone test, diagnosis of allergy, structure of cell membrane, purification of complex mixtures, identification of specialized cells, preparation of vaccines, increasing the effectiveness of medical substances (Edward, 1981). MAbs are used in applications against cancer cell-specific antigens which include an immunological response against targeted cancer cells. Availability of MAbs which recognizes immune cells antigen has resulted in improved diagnosis for lymphoma and leukemia. They are also being used in diagnosis of solid tumour especially for carcinoma of lungs, colon, and rectum. They are also useful in examining blood, sputum, biopsy samples of cancer cells or for materials discharged by cancer cells. At present MAbs are available for variety of cancers like ovarian, colorectal, lungs, etc (Beckman et al, 2007). MAbs interceded immunotherapy employs cells having cytotoxicity like monocytes and macrophages through antibody dependent cell cytotoxicity. MAbs binds complement proteins in cancer therapy which leads to direct cell toxicity that is complement dependent cytotoxicity (Carter, 2001). MAbs stops growth of tumour cells by blocking growth factors thus arresting the spread of tumour cells. MAbs not only detect cancer cells but also destroys them and clinical trials have revealed that MAbs stimulate partial reduction. Conjugate MAbs are combined with drugs and toxins and radioactive atoms are applied as delivery vehicles to take these substances through the body. MAbs flows in the body until it finds cancer cells with a matching antigen and delivers toxic substance to the place of the body. In chemotherapy, MAbs conjugate with chemotherapeutic drugs known as chemo labelled antibodies. The delivered drug causes damage to tumour and normal tissues. Clinical applicability of MAbs is because of its specificity and homogeneity. Another special feature of hybridoma production is that mixture of antigens can be used to produce specific antibodies. The treatment of cancer by MAbs has got highly advanced and its scope as therapeutic agent for untraced cancer has broadened. 2. REVIEW OF LITERATURE 2.1 Production of Monoclonal Antibody The production of MAbs by hybridoma technol ­ogy was first discovered by German scientist, Georges Kohler and Cesar Milstein of Argentina. In 1976 they developed a technique involving fusion of a cancerous (immortal) mouse B-Cell myeloma with an immunized mouse plasma cell by creating a hybrid cell/hybridoma (Blaine, 2012). The hybrid cells are clones of anti ­body producing cells against desired antigen and spread rapidly to generate large amounts of antibody. Hybridoma is capable of rapid circulation and high antibody exuding rates as in myeloma cells, and can maintain antibody genes of mouse spleen cells (figure 1.1).            Figure 1.1: Production of monoclonal antibodies 2.1.1 Outline of production of MAbs The basic approach for production of MAbs includes, viz., purification and characterization of the desired antigen in sufficient quantity, immunization of mice with purified antigen, culture of myeloma cells which are unable to synthesize hypoxanthine-gua ­nine-phosphoribosyl transferase (HGPRT) enzyme necessary for the salvage pathway of nucleic acids, exclusion of spleen cells from mice and its fusion with the myeloma cells, and following fusion growth of hybridomas in hypoxanthine aminop ­terin thymidine (HAT) medium where only the fused cells have the ability to grow. Because of lack of HGPRT, unfused myeloma cell has no ability to grow in this HAT medium, and as such cannot produce DNA. Because of short life spans unfused spleen cells can ­not grow, only fused hybrid cells/hybridomas can grow in HAT medium. Since spleen cell partners produce HGPRT, Hybrid cells have the ability to grow in the HAT medium. Hybrid cells clones are produced from single host cells and the antib odies exuded by the differ ­ent clones are then tested for their capability to combine to the antigen using an enzyme-linked immunosorbent assay (ELISA). And finally then the clone is selected for further use (Zola, 2010). 2.2 Types of Monoclonal Antibodies The various types of anti-cancer monoclonal antibodies are: 2.2.1 Naked monoclonal antibodies Naked MAbs are antibodies that work for themselves and there is no drug or radioactive material connected to them. For cancer treatment, these are the most common type of MAbs. A large number of naked MAbs are attached to antigens on cancer cells but a few of them performs either by joining antigens to the non-cancerous cells or to the free-floating proteins. Naked MAbs works in a diverse manner as elaborated below: Some of them increase patient’s immune response against cancer cells by joining to them and thereafter acting as an indicator for the body’s immune system to destroy them. For instance, Alemtuzumab used against leukemia (Lin T.S, 2008). Some of them targets immune system at checkpoints. While some work by joining and blocking the antigens which are important signals for cancer cells and other cells that help cancer cells grow or spread). E.g. Trastuzumab: used against breast and stomach cancer (Hudis, 2007). Conjugated monoclonal antibodies Conjugated MAbs are antibodies where MAbs are combined to other substance like chemotherapy drug, different type of toxin, or a radioactive particle. Here MAbs are used for taking these substances directly to the cancer cells and mingles in the body until it finds the targeted antigen and delivers the toxic substance at the required place thereby reducing or somewhat eliminating the chance of causing damage to normal cells in other parts of the body. These are also called as tagged, labelled, or loaded antibodies. They are divided into a variety of groups, as given below: Radiolabeled Antibodies These have minute radioactive particles joined to them. E.g. Ibritumomab tiuxetan, acts against CD20antigen (Knox S .Jet al, 1996). Chemolabeled antibodies These have strong chemotherapy (or other) drugs joined to them and are also known as antibody-drug conjugates (ADCs). E.g Brentuximab vedotin (acts against CD30 antigen) attaches to the chemo drug called MMAE. 2.3 Mechanism of Action MAbs apply their antitumor effects by various types of means of action: It directs the immune system to destroy cancer cells where the immune system destroys the foreign invaders in our body but it doesnt identify the cancer cells. MAbs are directed to join to particular parts of a cancer cell and marks cancer cells thereby making it simple for immune system to find like Rituximab (Rituxan) attached to a CD 20 protein on B cells. When Rituximab attaches to the protein on the B cells it makes the cancer cells more detectable to the immune system and make it convenient for it to attack. MAbs targeting Ccncer requires to attach to appropriate tumour cell surface antigens with adequate quantities and lead to destruction of targeted cells (Ignacio Met al, 2007). Mode of action include tumour cell toxicity via antibody-conjugate, modulation of host immune system (such as ADCC/CDC), and blockade of ligand combining and signalling perturbation. By combining with the cytokines or other proteins which are critical for cancer cells for maintaining their uncontrolled growth Cancer cells depend upon blood vessels to give them oxygen and nutrients required for their growth and to attract blood vessels cancer cells send growth signals. MAbs blocks these growth signals and prevent a tumour from maintaining a blood supply to stop growth. In other words, if a tumour has already instituted a network of blood vessels then it blocks the growth signals making the blood vessels to die and resulting in tumour to shrink. E.g. bevacizumab (Avastin) (Margeret VM et al, 2003). It targets a growth signal ,vascular endothelial growth factor (VEGF), which cancer cells sends to attract new blood vessels. It stops a tumours these signals and stops them from connecting with their targets. Delivery of radiation to cancer cells. MAbs are joined with radioactive particles to give radiations directly to the cancer cells. But the drawback is that by this method most of the healthy cells are damaged .E.g. Ibritumomab (Zevalin) It joins itself to the receptors on cancerous blood cells and subsequently delivers the radiation. Delivery of chemotherapy to cancer cells. MAbs are joined J with chemotherapy drugs to give radiations directly to the cancer cells.E.g. Ado-trastuzumab (Kadcyla). It joins to HER2 receptors present on the breast cancer cells and cancer cells consume these antibodies which in turn releases a few molecules of chemotherapy. chemotherapy damages only to the cancerous cells. 2.4 Side effects and limitation of monoclonal antibodies 2.4.1 Side-effects MAbs generally have small side effects unlike chemotherapy. Only a mild aller ­gic reaction or rashes may occur with first admin ­istration of the drug. Other common side-effects are fever, headache, weakness, chills, nausea with vom ­iting, and low blood pressure (Chames p et al, 2009). Whereas grave side-effects are infusion reaction, low blood cells count, heart problem, skin problem and bleeding. Else other side effects of MAbs are with the targeted antigens. Bevacizumab used against tumour blood vessel growth can result in kidney damage, high blood pressure, bleeding with poor wound heal ­ing, and blood clots (Scolnik, 2009). Cetuximab which is used against lungs cancer and head and neck cancer can result in severe infusion reaction and can cause serious rashes. Rituximab which is used against leukemia andlymphoma can cause renal toxicity and serum sickness. 2.4.2 Limitations A serious limitation is that MAbs drugs are most costly as there are only a few FDA regulated drugs which are available in the market. A good number of new MAb drugs are still under development process. Since generic competitors are not there, the sale of cost-effective MAbs is quite good. MAbs are most commercialized and marketed products. Due to huge cost, MAbs therapies are a financial burden on patients. With only proper health planning and step-wise periodic therapies the problem can be sorted. MAbs is a proven therapeutic agent and as acted as mulching cow for the pharma ­ceutical industry. The typical doses of MAb drugs needed for treatment are significantly higher than those required for other drugs. Thus, large-scale production that is cost-effective in man ­ufacturing processes is required. However, the huge demand to increase production of these drugs and the drive to lower the cost of these expensive medicines is a continuous challenge to the present industry. This will further improve the efficiency of manufacturing processes. These challenges are overcome by streamlining downstream processes to increase product quantities, to implement proper quality with high-concentration product formulations with sufficient stability, dose-effective products, to reduce the cost, to develop methodologies for time ­line MAb production, and to develop alternative delivery systems (Rohrer T et al, 2009). 2.5 Monoclonal Antibody Drugs used in Cancer The treatment of monoclonal antibody depends upon the type of cancer and drug you are receiving. Some of the drugs are used in combination with others treatment like chemotherapy and hormone therapy. MAb drugs are used to treat advanced cancer that does not respond to chemotherapy or cancer that had returned. Some of the mAb drugs are: Bevacizumab: Humanized; used against colorectal cancer, breast carcinoma, on-small cell lung cancer and renal carcinoma Rituximab: Chimeric; used against leukemia and lymphoma Cetuximab: Chimeric; used against EGFR-positive metastatic colorectal cancer and carcinoma of head and lungs Trastuzumab: Humanized; used against ERBB2-positive breast carcinoma 2.6 Diagnostic potential of monoclonal antibodies The development of monoclonal antibodies to has provided considerable research of interest. There are monoclonal antibodies which are directed against B cells, natural killer cells, granulocytes, monocytes and platelets. Abs which reacts with different antigens is available which have definite mechanism of action (Khemshead et al, 1983). Several antibodies hare available which react with progenitor cells and these have been used as an aid in the diagnosis of different leukaemias. Neuroblastoma and lymphoma cells may have the appearance of small round cell tumours and be indistinguishable morphologically. MAb react predominantly with these tumour types and used for such diagnostic distinction. Antibodies reacting against tumours when it is coupled with radio label may be used for radioisotope scanning and small metastasis may be visualised using this. MAbs are being used in clinical evaluations and promise to provide a new generation of targeting agent.

Sunday, October 13, 2019

Sophocles Antigone - The Stubborn Antigone and Creon :: Antigone essays

The Tragic Duo of Antigone and Kreon In the play Antigone, both Antigone and Kreon could be considered tragic heros. A tragic hero, defined by A Dictionary of Literary, Dramatic and Cinematic Terms, is someone who suffers due to a tragic flaw, or hamartia. This Greek word is variously translated as "tragic flaw" or "error" or "weakness". Kreon's hamartia, like in many plays, is hybris - Greek for overweening pride, arrogance, or excessive confidence. Kreon's hybris causes him to attempt to violate the laws of order or human rights, another main part of a tragic hero. Also, like all tragic heroes, Kreon suffers because of his hamartia and then realizes his flaw. The belief that Antigone is the hero is a strong one, but there is a stronger belief that Kreon, the Ruler of Thebes, is the true protagonist. Kreon's main and foremost hamartia was his hybris, or his extreme pride. Kreon was a new king, and he would never let anyone prove him wrong or let anyone change his mind once it was made. One main event that showed Kreon's hamartia and also caused the catastrophe was when he asked his son Haimon, who was engaged to marry Antigone, if he still loves his father. Haimon says he respects Kreon's ruling, but he feels, in this case, that Kreon was wrong. Haimon asks his father to take his advice and not have Antigone executed, but, because of Kreon's hybris, Kreon gets furious and makes the situation worse then it already was. He was way too proud to take advice from someone younger, and in his anger he decided to kill Antigone right away in front of Haimon's eyes. "'Just understand: You don't insult me and go off laughing. Bring her here! Let him see her. Kill her here, beside her bridegroom'" (Sophocles 919-921). This was too much for Haimon to take, and he runs out of the room, yelling, "'...her death will destroy others'" (Sophocles 908). Blinded by his pride and arrogance, Kreon takes that remark as a threat to himself, unknowing that it wasn't directed to himself, but was a suicide threat by his own son. Another example of Kreon's tragic pride is when the prophet, Teiresias, travels all the way to Thebes to tell Kreon very important news, but Kreon pride makes him ignore it and he accuses Teiresias of being bribed.